Measurement Of Body Fluid Compartment Volumes

Determinations of body fluid compartment volumes with measured using the bis impedivet impedimed limited brisbane australia were performed as described previously smith et al 2009. I have presented an oversimplified pictogram of this elegant process. Compartment volumes are measured by determining the volume of distribution of a tracer substance. The extracellular fluid compartment volume. Measuring total body water with radiolabelled tritium. Then make proportion calculation.

All exchanges of water and solutes with the external environment occur through the extracellular fluid ecf eg intravenous infusion and intake or loss via the gastrointestinal tract. The plasma volume is calculated by evans blue technique the proportion of plasma and hematocrit is by centrifugation. The volumes of the various body fluid compartments can be estimated in a healthy adult as shown in figure 1 3. Measuring the extracellular fluid volume with ionic tracer. Extracellular fluid 27 189 litres. Extracellular fluid volume measurement.

The intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranes. This volume is regulated by the movement of sodium. The fluid compartment volume. Intracellular fluid 33 231 litres. University of kentucky department of anesthesiology 5062 views 2943. Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrier.

A known amount of a tracer is added to a compartment. An approach to the measurement of body fluid compartment volumes in non steady conditions in the rat. The tracer is the patients own red cells which are tagged with radio chromium cr 51 red cellstypically a 10 ml sample of the subjects blood is incubated with a sodium chromate solution the label is taken up by the red cells and any excess in the solution is removed by dilution and centrifuging with removal of fluid. 221 the dilution principle. Fluid physiology 22 measurement of compartment volumes. A method has been developed by which body fluid volume changes can be assessed frequently after only one initial injection of the appropriate radioactive tracers.

Briefly previously anesthetized animals were placed in a prone position on a temperature controlled 37 01 c non conductive surface with their fore and hindlimbs besides their body and tails. This volume is regulated by the movement of free water. 20150921 fluid compartments regulation of ecf volume fluid replacement duration. If one were that way inclined one could also go on to read this indepth article by shoeller etal from 1980 full of thick juicy physiology. If plasma is x and its volume in body is y then plasmahematocrit100 the volume in body is v. Previous index next.

At 60 years of age you if male only have 50 body water instead of 60.